MS-HPS

Pharmastill Multieffect

The Pharmastill modular construction offers a wide range of configurations allowing optimum payback times. Standard models range from 60 to 22.000 lts/h output.
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The main features of Stilmas Pharmastill are:

Rapid start up: the distillate is produced after only few minutes after the switch on / Energy Saving: the best performances in terms of energy saving, thanks to an extremely accurate design of the condenser/evaporators and heat recovery system / High Flexibility: the production capacity can be varied by up to 80% without any plant modification / Unique purification system: gravitational purification principle for a better guarantee of distillate purity / Simple and clean mechanical construction: baffle – free decontamination chamber – no welding. Granting the best inspectability and, minimized corrosion risk, for the longest expected life of equipment / Extremely limited maintenance: no moving parts, expansion joints or mechanical seals. Compact construction and low weight: little extra head room needed for dismounting and inspection up to ten effects, for a maximum energetical efficiency.

 

Technical Description

Operating principle

The Pharmastill HPS is based on the ingenious combination of the “Thin Falling Film” and Multi-stage principles. The first effect is fed by an external energy source (Industrial Steam or Electrical energy). The pure steam generated in each effect and the non-evaporated water are fed to the subsequent one, operating at lower pressure; pure steam is condensed into WFI by vaporizing a new portion of feed water. Pharmastill is provided with one pre-heater for each column recovering the sensible heat of the distillate, and two final exchangers. In the final condenser a degassing system is also integrated, WFI conductivity is continuously measured and, in case of “out of spec”, the produced WFI is automatically discharged to the drain. On line TOC monitoring is also possible. The production capacity can be adjusted in the range of 60-100% simply by acting on the industrial steam pressure.

 

Technical Description

Construction characteristics

The plant is completely made with AISI 316L stainless steel. Standard finishing of the active surface is pickled and passivated; mirror or electropolishing can be made on request. Product (WFI) contact parts are manufactured with mechanically polished, 0.6 microns Ra surface finishing, with piping orbitally welded with sanitary flanges and pharmaceutical grade Teflon gasket. The design and construction of the decontamination chamber, which is a totally empty column, ensure the best inspectability. In this area, the absence of welding dramatically reduces the risk of corrosion, and a very long life of the equipment is therefore expected. Pre-heaters and exchanger are shell-and-tube type; double tube sheet execution is foreseen where contamination of the distillate is possible. The pipes are expanded into the plates, avoiding any welding for a totally hygienic execution, and a better resistance against dilatation stress. The general construction design, coupled with the described decontamination process, ensures a very high flexibility in equipment layout, together with an extremely limited space needed for maintenance.

Application fields

  • pharmaceutical
  • biotechnological
  • vet

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